High-Throughput Analysis in the Pharmaceutical Industry

High-Throughput Analysis in the Pharmaceutical Industry

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The introduction of combinatorial chemistry technology has increased the amount of compounds generated in a year from 50 to 2000. Conventional analytical approaches simply cannot keep up. These circumstances have caused drug discovery to take on the shape of a bottleneck, like traffic through a toll booth. In order to break the bottleneck, a corresponding revolutionary improvement to the conventional methodology must happen.The silyl derivatives were analyzed by GC/MS using a DB-5 column. Appropriate C13 labeled ... One example is Variana#39;s OMIX Tip for the Tomtec Quadra (see Figure 1.12), which is constructed by inserting a plug of OMIX C18 SPE material into the tip section of a Tomtec 450-mL pipette. This material is based ... No vacuum application or manual operator intervention was needed. In a typical extraction, anbsp;...

Title:High-Throughput Analysis in the Pharmaceutical Industry
Author: Perry G. Wang
Publisher:CRC Press - 2008-08-20

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